Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC537H879N133O153S4

DescriptionStandard

        MKNSNLFKIASITGVVSLFAIATFLMGSSEGIAGLASIDFSSGHQFALDLSTNLGISRKTAYVAIGVIMTTGDVLTILSLLAVVLGGTGLITAAMVATAKKLAKKYGKKYAAEW
    

Molecular Weight11774.78 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)4.58

Net Charge (pH 7.4) 4.29

Charge Density (pH 7.0) 0.0402

GRAVY Index0.72

Hydrophobic Moment 0.64

Boman Index0.32

Instability Index9.62

Aliphatic Index 116.49

Aromaticity 0.0789

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4536.55

LogP -41.62

H-bond Donors 162.0

H-bond Acceptors 163.0

Rotatable Bonds 397.0

Heavy Atoms 827.0

Ring Count 11.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305733 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyBacteriocin

Tax ID1402

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal