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MYP_133200
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Basic Information
Pm_mastoparan PMM
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C90H155N23O22
Standard
Sequence
INWKKIASIGKEVLKAL
Physicochemical Analysis
1911.33 Da
10.00
2.76
2.55
0.1623
0.25
0.65
0.13
-11.67
143.53
0.0588
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
749.41
-3.31
26.0
25.0
68.0
135.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0297336 VERIFIED: YES
Provenance & Taxonomy
Polistes dorsalis [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0305284 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis (
25.8 μM
MIC
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0312150 VERIFIED: YES
Provenance & Taxonomy
Polistes major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
7.3 μM
MIC
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0315895 VERIFIED: YES
Provenance & Taxonomy
Polistes major [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-negative
Escherichia coli
7.3 μM
MIC
RECORD: Rec_0317191 VERIFIED: YES
Provenance & Taxonomy
Polistes major major [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Rat erythrocytes
80 μM
IC50
PaperCerovský V, Slaninová J, Fučík V, et al. New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs. Peptides. 2008 Jun;29(6):992-1003. doi:10.1016/j.peptides.2008.02.007. PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
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