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MYP_133200
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Basic Information
Pm_mastoparan PMM
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C90H155N23O22
Standard
Sequence
INWKKIASIGKEVLKAL
Physicochemical Analysis
1911.33 Da
10.00
2.76
2.55
0.1623
0.25
0.65
0.13
-11.67
143.53
0.0588
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
749.41
-3.31
26.0
25.0
68.0
135.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0230950 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Polistes major major [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis
25.8 μM
MIC
PaperNew potent antimicrobial peptides from the venom of Polistinae wasps and their analogs
RECORD: Rec_0249227 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0258413 VERIFIED: YES
Provenance & Taxonomy
Polistes major [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Bacillus subtilis
25.8 μM
MIC
RECORD: Rec_0275180 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 64.7%, E 0.0%, T 17.6%, C 17.6% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic Anti-Gram-positive Anti-Gram-negative
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0276623 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rat blood cells
80 μM
IC50
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
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