Peptide Database

Peptide NameSLAY-screened peptide P1800

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC10H19N3O6S

DescriptionStandard

TCS

Molecular Weight309.34 Da

Isoelectric Point (pI)5.18

Net Charge (pH 7.0)-0.61

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.2039

GRAVY Index0.33

Hydrophobic Moment 0.12

Boman Index0.02

Instability Index6.67

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 161.98

LogP -3.33

H-bond Donors 7.0

H-bond Acceptors 7.0

Rotatable Bonds 8.0

Heavy Atoms 20.0

Ring Count 0.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391124 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/