Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 3.6

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC165H280N52O47S7

DescriptionStandard

        VGINVKCKHSGQCLKPCKDAGMRFGKCINGKCDCTPK
    

Molecular Weight3968.76 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.1556

GRAVY Index-0.45

Hydrophobic Moment 0.65

Boman Index-0.14

Instability Index4.49

Aliphatic Index 50.00

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1610.39

LogP -19.46

H-bond Donors 60.0

H-bond Acceptors 61.0

Rotatable Bonds 137.0

Heavy Atoms 271.0

Ring Count 4.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048170 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyPotassium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-27; 13-32; 17-34

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Pathogenesis-associated Host defense

RECORD: Rec_0225628 VERIFIED: NO