Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC445H736N128O125S8

DescriptionStandard

        MKLLVLFLAILLAIEEPVVSVECWMDGHCRLLCRDNEDSIIRCRNRKRCCVPSRYLTIEPVTIHGLLDWTTPQISTTVPQTKINKNRG
    

Molecular Weight10135.91 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0299

GRAVY Index0.02

Hydrophobic Moment 0.59

Boman Index-0.01

Instability Index63.15

Aliphatic Index 109.55

Aromaticity 0.0455

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4076.29

LogP -35.32

H-bond Donors 149.0

H-bond Acceptors 138.0

Rotatable Bonds 335.0

Heavy Atoms 706.0

Ring Count 13.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0119266 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence