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MYP_133109
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Basic Information
Defensin-A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
40 amino acids
C165H270N56O53S6
Standard
Sequence
ATCDLLSGFGVGDSACAAHCIARGNRGGYCNSKKVCVCRN
Physicochemical Analysis
4078.64 Da
8.68
2.82
2.49
0.0706
0.07
0.58
0.00
19.79
63.50
0.0500
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1769.66
-25.98
69.0
63.0
134.0
280.0
3.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019139 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
0.6-1.2 μM
MIC
PMID7633471;7568275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7633471/
RECORD: Rec_0044236 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Enterobacter cloacae beta12
1.2-2.4 μM
MIC
PMID7633471;7568275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7633471/
RECORD: Rec_0088486 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus rnegaterium
0.6-1.2 μM
MIC
PMID7633471;7568275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7633471/
RECORD: Rec_0090499 VERIFIED: NO
Provenance & Taxonomy
Aedes aegypti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPatent US 2008/0269122 A1 Evidence URLhttps://patents.google.com/patent/US20080269122A1/en PatentUS 2008/0269122 A1
RECORD: Rec_0126420 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Only one Gram-negative strain, Enterobacter cloacae f112
1.2-2.4 μM
MIC
PaperInsect immunity: isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti.
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