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MYP_133087
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Basic Information
Dermaseptin-S1 (1-15)[W3H]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C74H134N20O18S2
Standard
Sequence
ALHKTMLKKLGTMAL
Physicochemical Analysis
1656.11 Da
10.30
2.88
2.64
0.1920
0.39
0.48
0.15
16.37
117.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
617.92
-3.34
22.0
24.0
59.0
114.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259419 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Vero cells
100 μM
CC50
PaperPubMed PMID: 20718719 PMID20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718719/
RECORD: Rec_0282067 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
Candida albicans
45 μM
MIC
PMID18676150;20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18676150/
RECORD: Rec_0305632 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal Antifungal
HSV-1
PMID18676150;20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18676150/
RECORD: Rec_0341881 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 20718719 PMID20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718719/
RECORD: Rec_0347305 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
293TT(embryonic human culture cells)
100 μM
CC50
PaperPubMed PMID: 20718719 PMID20718719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20718719/
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