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MYP_133030
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Basic Information
Scorpine (defensins; Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
75 amino acids
C352H569N103O108S12
Standard
Sequence
GWINEEKIQKKIDERMGNTVLGGMAKAIVHKMAKNEFQCMANMDMLGNCEKHCQTSGEKGYCHGTKCKCGTPLSY
Physicochemical Analysis
8356.69 Da
8.58
2.97
2.50
0.0396
-0.64
0.54
-0.08
22.53
49.47
0.0533
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3436.82
-37.59
122.0
126.0
293.0
575.0
9.0
82.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0091772 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
39-62, 49-67, 53-69
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
1 μM
MIC
PMID10767415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10767415/
RECORD: Rec_0141357 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
10 μM
MIC
PMID10767415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10767415/
RECORD: Rec_0170283 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
Klebsiella pneumoniae
~10 μM
MIC
PaperScorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom
RECORD: Rec_0196748 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
Bacillus subtilis
1 μM
MIC
PaperScorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom
RECORD: Rec_0205273 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
1.0 μM
MIC
PMID10767415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10767415/
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