Peptide Database

Peptide NameSLAY-screened peptide P53

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC88H142N28O34S

DescriptionStandard

        CTGYHKLNARDTVNSDISSS
    

Molecular Weight2168.30 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.43

Charge Density (pH 7.0) -0.0081

GRAVY Index-0.76

Hydrophobic Moment 0.29

Boman Index-0.17

Instability Index42.82

Aliphatic Index 58.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1035.21

LogP -16.32

H-bond Donors 38.0

H-bond Acceptors 36.0

Rotatable Bonds 71.0

Heavy Atoms 151.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129409 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familyp53-derived

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/