‹ ›
MYP_133002
← PREVIOUS NEXT → BACK
Basic Information
Dermaseptin PD-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
31 amino acids
C141H241N39O43S3
Standard
Sequence
GMWSKIKETAMAAAKEAAKAAGKTISDMIKQ
Physicochemical Analysis
3266.85 Da
9.70
2.76
2.55
0.0891
-0.27
0.67
0.00
10.33
63.55
0.0323
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1344.14
-13.52
47.0
49.0
117.0
226.0
2.0
31.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0191813 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer
Candida albicans NCPF 1467
78.4 μM
MBC
PaperShi D et al. Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins. 2016;8:144. doi:10.3390/toxins8050144. PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0192120 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer
Human squamous lung carcinoma NCI-H157
MTT cell-proliferation assay; no inhibition observed at tested concentrations
PaperShi D et al. Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins. 2016;8:144. doi:10.3390/toxins8050144. PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0199134 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer
Human glioblastoma U251-MG
15.08 μM
IC50
PaperShi D et al. Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins. 2016;8:144. doi:10.3390/toxins8050144. PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0228474 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer
Staphylococcus aureus NCTC 10788
39.2 μM
MIC
PaperShi D et al. Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins. 2016;8:144. doi:10.3390/toxins8050144. PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0252391 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic Antimicrobial Antibacterial Antifungal Anticancer
horse erythrocytes
hemolysis assay
PaperShi D et al. Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins. 2016;8:144. doi:10.3390/toxins8050144. PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records · Page 2 of 4