Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC711H1132N188O217S16

DescriptionStandard

        MNLLMLTFVICGLLTQVTKGSFEPQKCWKNNIGCCRRRCLDTERYILLCRNKLSCCISIIMSYEYTRRPPFPVIHLEDITFDYSDMGSFTGSPVSKLSDLVTFDTHGETMTPETNTPETTMPPSKTTTSKTTMPPPSQMALTHN
    

Molecular Weight16298.76 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.18

Charge Density (pH 7.0) 0.0048

GRAVY Index-0.26

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index66.28

Aliphatic Index 67.64

Aromaticity 0.0764

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6457.63

LogP -69.21

H-bond Donors 232.0

H-bond Acceptors 237.0

Rotatable Bonds 525.0

Heavy Atoms 1132.0

Ring Count 27.0

Amide Bonds 152.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097152 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence