MYP_132959
AC3174
Binding / Molecular interaction
▸
Binding activity
Standard
39 amino acids
C185H283N49O61
Standard
HGEGTFTSDLSKQLEEEAVRLFIEWLKNGGPSSGAPPPS
4169.52 Da
4.70
-3.14
-3.40
-0.0805
-0.64
0.71
0.02
64.08
62.56
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1743.96
-19.71
58.0
59.0
133.0
295.0
9.0
40.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0141398
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Exendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Receptor-binding
binding to GLP-1 receptor
0.00066±0.00013 μM
IC50
Human plasma, in vitro; >18000 s
RECORD: Rec_0278230
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Exendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Regulates blood glucose
glucose lowering in db/db mice
ED50
Subcutaneously administion of 10µg/kg dose to Sprague Dawley rats, in vivo; 2520 s
RECORD: Rec_0364560
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Exendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Regulates blood glucose
glucose lowering in C57BL/6 mice
ED50
Subcutaneously administion of 100µg/kg dose to Sprague Dawley rats, in vivo; 2580 s