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MYP_132932
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Basic Information
Histatin 5 [R12I][K17N]
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C131H188N48O34
Standard
Sequence
DSHAKRHHGYKIKFHENHHSHRGY
Physicochemical Analysis
2979.20 Da
9.82
3.37
2.80
0.1404
-2.06
0.29
-0.44
17.21
20.42
0.1250
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1333.85
-14.11
48.0
44.0
98.0
213.0
10.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013843 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Histatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida glabrata 65C
100 μM
ED50
PMID10817697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10817697/
RECORD: Rec_0025011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Histatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida krusei
56.4 μM
ED50
PMID10817697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10817697/
RECORD: Rec_0032764 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 54.2%, C 45.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Antifungal Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0066089 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Histatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Cryptococcus neoformans CN2843
6.76 μM
ED50
PMID10817697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10817697/
RECORD: Rec_0072649 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Histatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Saccharomyces cerevisiae S288C
100 μM
ED50
PMID10817697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10817697/
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