Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length135 amino acids

Chemical FormulaC656H1071N183O203S6

DescriptionStandard

        METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEVSGPLLVSS
    

Molecular Weight14962.02 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-2.52

Net Charge (pH 7.4) -2.84

Charge Density (pH 7.0) -0.0187

GRAVY Index-0.26

Hydrophobic Moment 0.77

Boman Index-0.05

Instability Index37.67

Aliphatic Index 96.00

Aromaticity 0.0444

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6191.07

LogP -63.20

H-bond Donors 216.0

H-bond Acceptors 207.0

Rotatable Bonds 488.0

Heavy Atoms 1048.0

Ring Count 20.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0316636 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Tax ID9823

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal