Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length752 amino acids

Chemical FormulaC3543H5669N1057O992S22

DescriptionStandard

        MTETGPAMAPAAPAPGGTATACHAPRSRSCPKAEGGLLAPRCPPRGSALALLCLLLLLAACSPATGSSPGIKGRVTQRALEYGRHFGLELLRSQLQKEHELNLQGSYRPPFLGEIQYSVPRIHIQELQMNDSSVDFAEDVGVRLAVQGARIQLSADWSAQLGTFQDSGVVRLRVADLAVAVVLGLSVDEGGRPAVWAAGCDARGTDLHLEFQRGQSWLYNLLVPLLQRALRQQLNKQLCVELEKSIGRLEASLKRMRVSPQLDPFAAIDLSLLGRPAITAEHGDVSLKGEFFGVGRRRQSPFSPKPVGLPEAREPMVLLALTEFVANSAAFVYFTAGALRRNISGEALPRRFPIQLRTKSLGGFSPQLQELFPDLPMELQLSARRQPLLSCRPDALHGTLYGSAEAFVVLPNATRVPAFLLDIDANVTGKPSITGNRLGGTVRLTSLSVAQVTSQVGPLQVKKLENVLKFGLWLFGVPWANKRLRSGVPLPTPRGLSLVHPRLSLHEVGATPVPSPPRPWCHCVPPPSHPVFHAGLHAARHGPAVRALRPTAAGDPLTPSPSPFWGGPAGISPHPCSTWSPPSPRSRVPVPQLHAGTSPGGFCSAGGGRGHPTGWGLGAGGCQGRGSRTPPPPCPGTRSSRLARGMEPVATAPPHPHRQREPELGAAGGGRAQNPPQTPPRAWSILRGGVPVPVPVPVLVLVLVLVLVLGPSRVPPPNQRGAAPCPVSPNGDGHRGEDLGRGRAQEPGPSEK
    

Molecular Weight79649.83 Da

Isoelectric Point (pI)10.20

Net Charge (pH 7.0)30.18

Net Charge (pH 7.4) 28.64

Charge Density (pH 7.0) 0.0401

GRAVY Index-0.16

Hydrophobic Moment 0.75

Boman Index0.05

Instability Index61.22

Aliphatic Index 86.80

Aromaticity 0.0505

Extinction Coeff. Reduced 63940.00

Extinction Coeff. Oxidized 64815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0251439 VERIFIED: NO

Provenance & Taxonomy

OrganismCairina moschata domestica (Muscovy Duck (domestic type)) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria