Peptide Database

Peptide NameBeta-defensin 126

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC528H866N144O153S15

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCVPADRRANYPAFCVQTKTTRTSTVTATTATTTLMMTTASMSLMAPTPVSPTG
    

Molecular Weight12160.37 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.0767

GRAVY Index0.01

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index35.77

Aliphatic Index 67.66

Aromaticity 0.0631

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4753.29

LogP -51.10

H-bond Donors 174.0

H-bond Acceptors 178.0

Rotatable Bonds 398.0

Heavy Atoms 840.0

Ring Count 16.0

Amide Bonds 117.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379928 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence