Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC366H583N95O103S9

DescriptionStandard

        MKILYYLLHFLCYVTFILPATCNLVDADRCTKRKGLCKRNCLLSERQIDTCFSPTKICCSERLYEDESIF
    

Molecular Weight8250.70 Da

Isoelectric Point (pI)8.13

Net Charge (pH 7.0)1.51

Net Charge (pH 7.4) 1.11

Charge Density (pH 7.0) 0.0216

GRAVY Index0.09

Hydrophobic Moment 0.54

Boman Index-0.00

Instability Index48.50

Aliphatic Index 94.71

Aromaticity 0.1143

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3212.58

LogP -25.33

H-bond Donors 122.0

H-bond Acceptors 115.0

Rotatable Bonds 274.0

Heavy Atoms 573.0

Ring Count 11.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209820 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence