Peptide Database

Peptide NameLutzicidin (Cathelicidin-related antimicrobial peptide) (CRAMP) (Vipericidin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC978H1528N250O296S6

DescriptionStandard

        MQGFFWKTLLVVALCGTSSSLAHRPLSYGEALELALSVYNSKAGEESLFRLLEAVPQPEWDPLSEGSQQLNFTIKETVCQVEEERPLEECGFQEDGVVLECTGYYFFGETPPVVVLTCVPVGGVEEEEEDEEEQKAEVEKDEEKEDEEKDRPKRVKRFKKFFKKLKNNVKKRVKKFFRKPRVIGVTIPF
    

Molecular Weight21716.48 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-9.39

Net Charge (pH 7.4) -9.82

Charge Density (pH 7.0) -0.0497

GRAVY Index-0.54

Hydrophobic Moment 0.89

Boman Index-0.08

Instability Index54.17

Aliphatic Index 75.66

Aromaticity 0.1005

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8828.09

LogP -96.43

H-bond Donors 302.0

H-bond Acceptors 294.0

Rotatable Bonds 702.0

Heavy Atoms 1530.0

Ring Count 33.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0183723 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops lutzi [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetGram-negative and Gram-positive bacteria