Peptide Database

Peptide NameVWAS

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC22H31N5O6

DescriptionStandard

        VWAS
    

Molecular Weight461.51 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) -0.0665

GRAVY Index1.07

Hydrophobic Moment 0.20

Boman Index0.58

Instability Index-30.07

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 186.64

LogP -0.76

H-bond Donors 7.0

H-bond Acceptors 6.0

Rotatable Bonds 11.0

Heavy Atoms 33.0

Ring Count 2.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279042 VERIFIED: YES

Provenance & Taxonomy

OrganismAllium sativum [Plant]

Tax ID4682

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory Antihypertensive Antioxidant Anti-inflammatory

TargetACE; spontaneously hypertensive rat

Activity31.38 μM

MethodIC50