Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2315H3622N586O679S17

DescriptionStandard

        MTLTPHTLGTPHTREEEPGIRAALTRNGLGQASHVLTGWIQSRLSTIHLPEVQGEVDIGIGAVYYVLHDMSVVQCDLPEPEVAPTEGTGISVLVSGVSIKIQGSWNTNFGIIHDGGWFELAVFDILLKSTLQLGSDYGARLSVTALFCQAEVGNVDINFHGGASFIFQPFVSHFTGRIISEIQVKICPAFNQAVESLESHLAAMEVSIPVSPFVFVKIPLTESPIVTDSGIEVDIKGIFYSIQNPTEPPFPPNHFALQWQDDCMLAAGASEFCVNTVAFAHFTAGALQINITDSMIPKTSPVHLNTSQFGPFIPQLPKLFPNRLMQVLLYASESPHVSLRTNMIIVEVSAEAKVFAVQPDSSLAPLFKLDMEISLSGKVFIEGQLLKGSLTLNNFTMTLGSSEIGQFEIGVMQNTMKTALNMVVLPQLNGKLRDGLPLPSPKGFSLANAKLTVGEGFLALTTDIEAPYEDKL
    

Molecular Weight51072.15 Da

Isoelectric Point (pI)4.98

Net Charge (pH 7.0)-19.34

Net Charge (pH 7.4) -20.38

Charge Density (pH 7.0) -0.0410

GRAVY Index0.22

Hydrophobic Moment 0.58

Boman Index0.21

Instability Index36.07

Aliphatic Index 100.36

Aromaticity 0.0805

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420124 VERIFIED: NO

Provenance & Taxonomy

OrganismChanos chanos (Milkfish) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria