Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC164H277N49O48S4

DescriptionStandard

        IINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCST
    

Molecular Weight3831.51 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.1094

GRAVY Index-0.18

Hydrophobic Moment 0.63

Boman Index-0.09

Instability Index55.23

Aliphatic Index 88.82

Aromaticity 0.0588

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1603.84

LogP -16.92

H-bond Donors 61.0

H-bond Acceptors 56.0

Rotatable Bonds 130.0

Heavy Atoms 265.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108057 VERIFIED: YES

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)