Peptide Database

Peptide NamePumilarin (Circular bacteriocin) (Enterocin AS-48-like) (Head-to-tail cyclized peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC519H857N131O141S3

DescriptionStandard

        MTETKNEIKLHVLFGALAVGFLMLALFSFSLQMLPVADLAKEFGIPGSVAAVVLNVVEAGGAVTTIVSILTAVGSGGLSLIAAAGKETIRQYLKNEIKKKGRKAVIAW
    

Molecular Weight11284.34 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)3.60

Net Charge (pH 7.4) 3.30

Charge Density (pH 7.0) 0.0333

GRAVY Index0.72

Hydrophobic Moment 0.65

Boman Index0.30

Instability Index15.46

Aliphatic Index 125.56

Aromaticity 0.0648

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4301.43

LogP -32.73

H-bond Donors 149.0

H-bond Acceptors 149.0

Rotatable Bonds 382.0

Heavy Atoms 794.0

Ring Count 11.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249090 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus safensis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. pumilus (Gram-positive)

RECORD: Rec_0328973 VERIFIED: YES