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MYP_132701
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Basic Information
Pumilarin (Circular bacteriocin) (Enterocin AS-48-like) (Head-to-tail cyclized peptide)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
108 amino acids
C519H857N131O141S3
Standard
Sequence
MTETKNEIKLHVLFGALAVGFLMLALFSFSLQMLPVADLAKEFGIPGSVAAVVLNVVEAGGAVTTIVSILTAVGSGGLSLIAAAGKETIRQYLKNEIKKKGRKAVIAW
Physicochemical Analysis
11284.34 Da
9.63
3.60
3.30
0.0333
0.72
0.65
0.30
15.46
125.56
0.0648
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4301.43
-32.73
149.0
149.0
382.0
794.0
11.0
112.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044378 VERIFIED: YES
Provenance & Taxonomy
Bacillus safensis [Bacterium]
Bacteriocin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
S. pneumoniae (Gram-positive)
PMID25767247;29177092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25767247/
RECORD: Rec_0073572 VERIFIED: NO
Provenance & Taxonomy
Bacillus safensis [Bacterium]
Circular bacteriocin
Structure & Mods
head-to-tail cyclic bacteriocin scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A6I0G390/entry
RECORD: Rec_0127085 VERIFIED: YES
Provenance & Taxonomy
Bacillus safensis [Bacterium]
Bacteriocin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
B. cereus (Gram-positive)
PMID25767247;29177092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25767247/
RECORD: Rec_0127455 VERIFIED: NO
Provenance & Taxonomy
Bacillus pumilus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A0H1S913/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0216625 VERIFIED: YES
Provenance & Taxonomy
Bacillus safensis [Bacterium]
Bacteriocin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
M. flavus (Not characterize)
PMID25767247;29177092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25767247/
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