Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC525H841N149O144S10

DescriptionStandard

        MTPFMLTLTVLLLLSQAIPGSTEKCWNLHGNCREECHKDETVFIFCPSGKLCCVKPKFQPKITRQRKRINIPKIYMEPLKTCNSHRNLEKKEQSWRDHYTG
    

Molecular Weight11864.86 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)7.79

Net Charge (pH 7.4) 7.24

Charge Density (pH 7.0) 0.0771

GRAVY Index-0.58

Hydrophobic Moment 0.54

Boman Index-0.12

Instability Index54.96

Aliphatic Index 71.39

Aromaticity 0.0792

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4742.67

LogP -42.93

H-bond Donors 170.0

H-bond Acceptors 166.0

Rotatable Bonds 397.0

Heavy Atoms 828.0

Ring Count 21.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299439 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

FamilyDefensin

Tax ID59463

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence