Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length433 amino acids

Chemical FormulaC2167H3438N568O596S16

DescriptionStandard

        MARWAALVVLVAVGTAVAVATNPGFVARITQKGLDYVCQEGVAKLRKELEKINIPDISGKVKMKPFGKGHYSIYSKTSGNFDLRVEGISISADLKLGSDPGSGHPTVTCPSCNSNINSVHVGISGSKLGWLIRLFRSKIESALRRAINSKICNVVANSVSSKLQPYFQTLPVTAKIDAVAGIDYSLVAPPTATADSLDVKLKGEFFRLAYRTPPPFAPPALAFPTDHHHMVYLGISEYFFNTAGLVYHTAGVMRLAFTDDMIPQESKFRLTTRSFRSFLPQVDKKFPNMKMQLFLSVSSPPQLAVDPTGLTLTPTLEAQAFAVFPNSSLTSLFRLGLIMNISVVVGIKSDRLVGELMMNKLHLELKHSAIGYFPVQLLEAVMNYFVPTVLLPKVNERLQRGIPLPLPAHIQLSNMVLRPYQDFLLFGTDVKYG
    

Molecular Weight47496.97 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)15.35

Net Charge (pH 7.4) 14.48

Charge Density (pH 7.0) 0.0354

GRAVY Index0.15

Hydrophobic Moment 0.83

Boman Index0.14

Instability Index34.09

Aliphatic Index 99.49

Aromaticity 0.0901

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425526 VERIFIED: NO

Provenance & Taxonomy

OrganismOrycteropus afer afer [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria