Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC431H692N118O117S9

DescriptionStandard

        MKMLCIFLTFVFTVSSGPSVPQKKTREVAERKRECQLVRGACKSECNTWEYVHYYCDVKPCCVVRDYQKPIINKITTKLYRK
    

Molecular Weight9687.41 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.1039

GRAVY Index-0.35

Hydrophobic Moment 0.72

Boman Index-0.12

Instability Index45.23

Aliphatic Index 72.32

Aromaticity 0.1098

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3841.33

LogP -32.61

H-bond Donors 143.0

H-bond Acceptors 136.0

Rotatable Bonds 323.0

Heavy Atoms 675.0

Ring Count 15.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413094 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence