Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length203 amino acids

Chemical FormulaC1032H1593N245O301S8

DescriptionStandard

        MLHLAFSEYFFQTSSFAYYTAGAFSITIAEETCSYFNINTDMFGSIIPEVAKYSVTPYPVMLKLTATEIPIISLEQDSFTAEIRGSMEVFAVLPDSATQSLFTINIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLPSLANVTLTRPHITIVQGYMLISTDVHYKH
    

Molecular Weight22504.67 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-7.06

Net Charge (pH 7.4) -7.60

Charge Density (pH 7.0) -0.0348

GRAVY Index0.38

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index46.46

Aliphatic Index 103.35

Aromaticity 0.1182

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068330 VERIFIED: NO

Provenance & Taxonomy

OrganismAccipiter nisus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria