Peptide Database

Peptide NameHBD3 [C11,18,23,33,40,41W]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC264H407N81O59

DescriptionStandard

        GIINTLQKYYWRVRGGRWAVLSWLPKEEQIGKWSTRGRKWWRRKK
    

Molecular Weight5659.56 Da

Isoelectric Point (pI)11.65

Net Charge (pH 7.0)10.76

Net Charge (pH 7.4) 10.54

Charge Density (pH 7.0) 0.2391

GRAVY Index-1.15

Hydrophobic Moment 0.69

Boman Index-0.29

Instability Index51.43

Aliphatic Index 67.11

Aromaticity 0.1778

Extinction Coeff. Reduced 35980.00

Extinction Coeff. Oxidized 35980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2344.34

LogP -15.26

H-bond Donors 89.0

H-bond Acceptors 70.0

Rotatable Bonds 188.0

Heavy Atoms 404.0

Ring Count 15.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415645 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa ATCC 27853

Activity5.1 μg/mL

MethodLC50

RECORD: Rec_0418507 VERIFIED: YES