Peptide Database

Peptide NameSLAY-screened peptide P313

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC105H155N31O35S

DescriptionStandard

        MQPHRRNYNTYSLFTDPSDT
    

Molecular Weight2443.61 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-0.41

Net Charge (pH 7.4) -0.68

Charge Density (pH 7.0) -0.0206

GRAVY Index-1.53

Hydrophobic Moment 0.40

Boman Index-0.33

Instability Index48.04

Aliphatic Index 19.50

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1096.60

LogP -13.85

H-bond Donors 38.0

H-bond Acceptors 37.0

Rotatable Bonds 74.0

Heavy Atoms 172.0

Ring Count 6.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294768 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/