Peptide Database

Peptide NameW9F,W11V (mutant of Def-DAA defensin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC178H288N60O51S6

DescriptionStandard

        ATCDLASKFNVNHTLCAAHCIARRYRGGYCNSKAVCVCR
    

Molecular Weight4276.95 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)4.91

Net Charge (pH 7.4) 4.52

Charge Density (pH 7.0) 0.1258

GRAVY Index0.02

Hydrophobic Moment 0.52

Boman Index-0.07

Instability Index15.87

Aliphatic Index 67.69

Aromaticity 0.0769

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1814.07

LogP -22.88

H-bond Donors 72.0

H-bond Acceptors 64.0

Rotatable Bonds 138.0

Heavy Atoms 295.0

Ring Count 5.0

Amide Bonds 41.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0055518 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus strain 21

Activity4-8 μg/mL

MethodIC90

RECORD: Rec_0415042 VERIFIED: YES