Peptide Database

Peptide NameBacteriocin nukacin (Nukacin KQ-1; Nukacin KQU-131)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC133H206N36O38S5

DescriptionStandard

        KKKSGVIPTVSHDCHMNTFQFMFTCCS
    

Molecular Weight3077.60 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0705

GRAVY Index-0.09

Hydrophobic Moment 0.27

Boman Index0.05

Instability Index19.27

Aliphatic Index 35.93

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1191.41

LogP -13.42

H-bond Donors 44.0

H-bond Acceptors 47.0

Rotatable Bonds 100.0

Heavy Atoms 212.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128059 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus hominis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0151966 VERIFIED: YES

Provenance & Taxonomy

OrganismStaphylococcus hominis [Bacterium]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)