Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length464 amino acids

Chemical FormulaC2289H3686N596O641S17

DescriptionStandard

        MFLSVRLLLLLAVLAPVTSTTNPGVKVKLTQKGLEYGRQLGMIQIQQKLKTIKVPDISGSQKVSPIGKVQYSLTNMHIVNVGLPKSGLGLVPGTGVRLSIGNAFISLNGNWRVKYLRFIKDHGSFDLKVSGLTIGTTIIIQSDETGRPRVSSTNCAATVGGADIKFHGGASWLYNLFRNFIDKALRSALQKQICPLVVDAISDLNPQLKTLNVLAKVDQYAEIEYSMVSSPTVSKSSIDFGLKGVFYNIGKHQEPPFSPAVFSLPPQINNMLYVGMSTFTINSAAFVYNSAGALSLYITDDMIPAGSPIRLNTRTFGAFIPQLSKLFPGLMMKLLVKTAKTPVISFQPNNVTVQASGTVTAYAIQPNATLSPLFVLNLETSVSTRVFVSGMRVAGAVTLNKMDVTLGTSYVGAFQVKSLDNILQMVVKIVVIPKLNGEFMHFKMNSAVIHLQIREAQFVMLFTS
    

Molecular Weight50356.46 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)21.00

Net Charge (pH 7.4) 20.37

Charge Density (pH 7.0) 0.0453

GRAVY Index0.27

Hydrophobic Moment 0.80

Boman Index0.18

Instability Index29.56

Aliphatic Index 105.60

Aromaticity 0.0819

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262214 VERIFIED: NO

Provenance & Taxonomy

OrganismSphaeramia orbicularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria