Peptide Database

Peptide NamePhospholipase A2 homolog 1 (svPLA2 homolog) (Myotoxin I)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC676H1087N185O200S18

DescriptionStandard

        MRTLWIMAVLLVGVEGSLVELGKMILQETGKNPLTSYGAYGCNCGVGGRGKPKDATDRCCYVHKCCYKKMTDCDPKKDRYSYSWKDKTIVCGEKNSCLKELCECDKAVAICLRENLDTYNKKYKNNYLKPFCKKADAC
    

Molecular Weight15583.15 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)8.45

Net Charge (pH 7.4) 7.92

Charge Density (pH 7.0) 0.0612

GRAVY Index-0.48

Hydrophobic Moment 0.57

Boman Index-0.11

Instability Index28.46

Aliphatic Index 67.10

Aromaticity 0.0870

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 25285.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6271.37

LogP -60.63

H-bond Donors 232.0

H-bond Acceptors 228.0

Rotatable Bonds 531.0

Heavy Atoms 1079.0

Ring Count 19.0

Amide Bonds 145.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421042 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops atrox [Animal]

FamilyPhospholipase A2; Group II subfamily; K49 sub-subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Cytolytic Toxin Non-hemolytic

TargetNo Target Organism Found