Peptide Database

Peptide Namealpha-9 gliadin epitope homolog (p57-p68; Q64 and E65 (tTG-treated form))

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Venom / Toxin ▸ General toxin ▸ Celiac toxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H102N16O20

DescriptionStandard

        QLQPFPQQELPY
    

Molecular Weight1487.65 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1032

GRAVY Index-1.10

Hydrophobic Moment 0.22

Boman Index-0.02

Instability Index148.68

Aliphatic Index 65.00

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 586.94

LogP -3.54

H-bond Donors 16.0

H-bond Acceptors 19.0

Rotatable Bonds 43.0

Heavy Atoms 106.0

Ring Count 5.0

Amide Bonds 15.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0076733 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: Q64; Reported substitutions/positions: E65

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay

RECORD: Rec_0425489 VERIFIED: YES