Peptide Database

Peptide NameDermaseptin sVIII

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Antiviral

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC141H239N39O39S

DescriptionStandard

        ALWKTMLKKLGTVALHAGKAALGAAADTISQ
    

Molecular Weight3136.71 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.63

Charge Density (pH 7.0) 0.0929

GRAVY Index0.43

Hydrophobic Moment 0.53

Boman Index0.23

Instability Index2.25

Aliphatic Index 110.65

Aromaticity 0.0323

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1246.18

LogP -11.24

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 106.0

Heavy Atoms 220.0

Ring Count 3.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360888 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0403444 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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