Peptide Database

Peptide NameHuman beta defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC190H314N58O45S6

DescriptionStandard

        IRNPVTCIRSGAICHPGFCPGRYKHIGVCGVPLIKCCKKP
    

Molecular Weight4323.28 Da

Isoelectric Point (pI)9.55

Net Charge (pH 7.0)6.87

Net Charge (pH 7.4) 6.47

Charge Density (pH 7.0) 0.1718

GRAVY Index0.17

Hydrophobic Moment 0.63

Boman Index0.07

Instability Index45.82

Aliphatic Index 82.75

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1605.19

LogP -14.49

H-bond Donors 61.0

H-bond Acceptors 60.0

Rotatable Bonds 135.0

Heavy Atoms 299.0

Ring Count 9.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058329 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)