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MYP_132342
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Basic Information
Kassiniatuerin-3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C113H177N27O25
Standard
Sequence
FIQHLIPLIPHAIQGIKDIF
Physicochemical Analysis
2313.78 Da
6.92
-0.07
-0.37
-0.0033
0.88
0.62
0.46
-1.87
161.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
805.50
-0.81
25.0
27.0
73.0
165.0
6.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0288763 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion of the African Frog,Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H23
4.52 μM
IC50
PaperPubMed PMID: 32630734 PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0296630 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human lung adenocarcinoma NCI-H23
4.52 μM
IC50
PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0305813 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion of the African Frog,Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 32630734 PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0329206 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
512 μM
MBC
PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0329566 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans
64-128 μM
MIC
PaperA Novel Antimicrobial Peptide (Kassinatuerin-3) Isolated from the Skin Secretion of the African Frog,Kassina senegalensis
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