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MYP_132342
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Basic Information
Kassiniatuerin-3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C113H177N27O25
Standard
Sequence
FIQHLIPLIPHAIQGIKDIF
Physicochemical Analysis
2313.78 Da
6.92
-0.07
-0.37
-0.0033
0.88
0.62
0.46
-1.87
161.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
805.50
-0.81
25.0
27.0
73.0
165.0
6.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0226369 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion of the African Frog,Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-251MG
13.20 μM
IC50
PaperPubMed PMID: 32630734 PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0226703 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human glioblastoma U251-MG
13.2 μM
IC50
PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0270673 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human squamous lung carcinoma NCI-H157
21.54 μM
IC50
PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0271806 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion of the African Frog,Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H460
1.67 μM
IC50
PaperPubMed PMID: 32630734 PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
RECORD: Rec_0283365 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
128 μM
MIC
PMID32630734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32630734/
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