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MYP_132339
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Basic Information
gHH3
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
34 amino acids
C169H293N49O49
Standard
Sequence
NADIIKSLIRKTIINASKNTASLSILQHLYVLRS
Physicochemical Analysis
3795.43 Da
10.45
3.84
3.58
0.1131
0.22
0.68
0.05
36.06
143.53
0.0294
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1625.66
-16.46
58.0
54.0
132.0
267.0
2.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0353082 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0369857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Newcastle disease virus(NDV):inhibition of viral infection in chicken embryo fibroblasts
52.9±0.9 μM
IC50
PaperPubMed PMID: 24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0416365 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-NDV Entry inhibition
Newcastle disease virus(NDV)
52.9±0.9 μM
IC50
Mammalian: 1.4 h; Yeast: 3 min; E. coli: >10 h
PaperIn vitro and in vivo broad antiviral activity of peptides homologous to fusion glycoproteins of Newcastle disease virus and Marek's disease virus. | Chi XJ, Wang XJ, Wang CY, Cui XJ, Wang XJ. | J Virol Methods. 2014 Apr;199:11-6. | DOI:10.1016/j.jviromet.2013.12.022 | PMID:24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
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