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MYP_132339
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Basic Information
gHH3
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
34 amino acids
C169H293N49O49
Standard
Sequence
NADIIKSLIRKTIINASKNTASLSILQHLYVLRS
Physicochemical Analysis
3795.43 Da
10.45
3.84
3.58
0.1131
0.22
0.68
0.05
36.06
143.53
0.0294
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1625.66
-16.46
58.0
54.0
132.0
267.0
2.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108172 VERIFIED: YES
Provenance & Taxonomy
Gallid alphaherpesvirus 2 [Virus]
Virus-derived peptide
10390;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Marek's disease virus (Virus entry); CEF
12 μM
Plaque assay
PaperStructural characteristics and antiviral activity of multiple peptides derived from MDV glycoproteins B and H. | Wang X, Chi X, Wang M. | Virol J. 2011 | PMID:21518442 PMID21518442 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21518442/
RECORD: Rec_0122794 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0182732 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-MDV Entry inhibition
Marek's disease virus(MDV)
37.5±1.2 μM
IC50
Mammalian: 1.4 h; Yeast: 3 min; E. coli: >10 h
PaperIn vitro and in vivo broad antiviral activity of peptides homologous to fusion glycoproteins of Newcastle disease virus and Marek's disease virus. | Chi XJ, Wang XJ, Wang CY, Cui XJ, Wang XJ. | J Virol Methods. 2014 Apr;199:11-6. | DOI:10.1016/j.jviromet.2013.12.022 | PMID:24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0239310 VERIFIED: YES
Provenance & Taxonomy
Gallid alphaherpesvirus 2 [Virus]
Virus-derived peptide
10390;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Marek's disease virus (Virus entry); CEF
12200 μM
Plaque assay
PaperInteraction domain of glycoproteins gB and gH of Marek's disease virus and identification of an antiviral peptide with dual functions. | Chi XJ, Lu YX, Zhao P, Li CG, Wang XJ, Wang M. | PLoS One. 2013 | PMID:23405092 PMID23405092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23405092/
RECORD: Rec_0331402 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Marek's disease virus(MDV):inhibition of viral infection in chicken embryo fibroblasts
37.5±1.2 μM
IC50
PaperPubMed PMID: 24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
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