Peptide Database

Peptide NameBacteriocin helveticin-J

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length333 amino acids

Chemical FormulaC1660H2550N460O523S6

DescriptionStandard

        MKHLNETTNVRILSQFDMDTGYQAVVQKGNVGSKYVYGLQLRKGATTILRGYRGSKINNPILELSGQAGGHTQTWEFAGDRKDINGEERAGQWFIGVKPSKIEGSKIIWAKQIARVDLRNQMGPHYSNTDFPRLSYLNRAGSNPFAGNKMTHAEAAVSPDYTKFLIATVENNCIGHFTIYNLDTINEKLDEKGNSEDVNLETVKYEDSFIIDNLYGDDNNSIVNSIQGYDLDNDGNIYISSQKAPDFDGSYYAHHKQIVKIPYYARSKESEDQWRAVNLSEFGGLDIPGKHSEVESIQIIGENHCYLTVAYHSKNKAGENKTTLNEIYELSWN
    

Molecular Weight37511.16 Da

Isoelectric Point (pI)5.72

Net Charge (pH 7.0)-7.60

Net Charge (pH 7.4) -8.47

Charge Density (pH 7.0) -0.0228

GRAVY Index-0.66

Hydrophobic Moment 0.73

Boman Index-0.05

Instability Index27.37

Aliphatic Index 75.86

Aromaticity 0.1021

Extinction Coeff. Reduced 55810.00

Extinction Coeff. Oxidized 55935.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344332 VERIFIED: NO

Provenance & Taxonomy

OrganismLactobacillus helveticus [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetLactobacillus

MethodQualitative functional evidence