Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC925H1461N245O276S4

DescriptionStandard

        VLPNPVMVDPLPDDTGLHATTSPAPEEKDFADYILILPFPDIPPIYIYLSKPPVEFLEVELYSDFKRRSRQGKYEADHMPSRAAVDAYLRANYPLLDDAEILALTDQVAAIVIPKEIHQKISETYGKRNSPAQIELDSRNLRAAVDRNLDAIKPALKEYGATEGQIEAARAKMHKLNGGMGLYK
    

Molecular Weight20558.23 Da

Isoelectric Point (pI)5.26

Net Charge (pH 7.0)-5.89

Net Charge (pH 7.4) -6.36

Charge Density (pH 7.0) -0.0320

GRAVY Index-0.38

Hydrophobic Moment 0.58

Boman Index-0.01

Instability Index58.09

Aliphatic Index 93.42

Aromaticity 0.0761

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 14900.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8289.06

LogP -88.20

H-bond Donors 277.0

H-bond Acceptors 278.0

Rotatable Bonds 669.0

Heavy Atoms 1450.0

Ring Count 35.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371463 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli