Peptide Database

Peptide NameTRH-Potentiating peptide-10

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC54H75N11O18S

DescriptionStandard

        SFPWMESDVT
    

Molecular Weight1198.30 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.75

Charge Density (pH 7.0) -0.2536

GRAVY Index-0.29

Hydrophobic Moment 0.19

Boman Index0.18

Instability Index59.83

Aliphatic Index 29.00

Aromaticity 0.2000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 467.51

LogP -3.65

H-bond Donors 16.0

H-bond Acceptors 17.0

Rotatable Bonds 34.0

Heavy Atoms 84.0

Ring Count 4.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145277 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal] [Animal]; Rattus norvegicus [Animal]

Tax ID9913;10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Peptide Potentiator

RECORD: Rec_0180836 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyTRH-potentiating peptide

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0268113 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0283702 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/