Peptide Database

Peptide NameNeuropeptide RFRP-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC195H303N51O52S2

DescriptionStandard

        SLNFEELKDWGPKNVIKMSTPAVNKMPHSFANLPLRF
    

Molecular Weight4257.93 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.55

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0419

GRAVY Index-0.40

Hydrophobic Moment 0.53

Boman Index0.02

Instability Index70.48

Aliphatic Index 73.78

Aromaticity 0.1081

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1651.39

LogP -13.14

H-bond Donors 54.0

H-bond Acceptors 57.0

Rotatable Bonds 137.0

Heavy Atoms 300.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132771 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0326838 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyFMRFamide related peptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0329949 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0418959 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNeuropeptide NPSF

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour