Peptide Database

Peptide NametatM2NX

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC190H323N71O45S

DescriptionStandard

        YGRKKRRQRRRGSREPGEMLPRKLKRVLRQEFWV
    

Molecular Weight4354.11 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.76

Net Charge (pH 7.4) 10.55

Charge Density (pH 7.0) 0.3166

GRAVY Index-1.79

Hydrophobic Moment 1.01

Boman Index-0.75

Instability Index102.16

Aliphatic Index 51.47

Aromaticity 0.0882

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1983.45

LogP -18.31

H-bond Donors 75.0

H-bond Acceptors 57.0

Rotatable Bonds 154.0

Heavy Atoms 307.0

Ring Count 6.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038926 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Ion channel modulation Signaling peptide

TargetTRPM2 (Human)

Activity396 nM

MethodIC50