Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length104 amino acids

Chemical FormulaC549H859N143O142S6

DescriptionStandard

        LSVMKPYLMTIVILLILVHKTSALKKSKTQPTIKCQQGYGICRERCRHDETETHFCRNKGKLPIFLSFWVPSSILKATNTGPYHIVSFYLSSFSAFHFHIEGPL
    

Molecular Weight11926.96 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)8.24

Net Charge (pH 7.4) 7.65

Charge Density (pH 7.0) 0.0793

GRAVY Index0.03

Hydrophobic Moment 0.42

Boman Index0.10

Instability Index37.54

Aliphatic Index 91.83

Aromaticity 0.1154

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4524.54

LogP -35.31

H-bond Donors 163.0

H-bond Acceptors 162.0

Rotatable Bonds 389.0

Heavy Atoms 840.0

Ring Count 25.0

Amide Bonds 108.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0174121 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Animal]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence