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MYP_132232
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Basic Information
Potassium channel toxin alpha-KTx 12.1
Annotation / Sequence feature ▸ Nuclear export signal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Membrane / Ion-channel modulation ▸ Ion channel inhibition
Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
40 amino acids
C188H287N57O55S9
Standard
Sequence
WCSTCLDLACGASRECYDPCFKAFGRAHGKCMNNKCRCYT
Physicochemical Analysis
4514.22 Da
8.50
2.77
2.39
0.0692
-0.32
0.59
-0.11
44.62
29.50
0.1250
8480.00
8980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1817.12
-21.37
73.0
68.0
144.0
309.0
8.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0177249 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Potassium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-5; 10-31; 16-36; 20-38
Bio-Activity Profile
Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense
PaperPDB 1C55 structural record; NMR; chain A; residues 1-40
RECORD: Rec_0288058 VERIFIED: NO
Provenance & Taxonomy
Tityus trivittatus [Animal]; Tityus serrulatus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
2-5; 10-31; 16-36; 20-38
Bio-Activity Profile
Toxin