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MYP_132220
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Basic Information
D-SMAP-29-1
Anticancer
Anticancer ▸ Anti-proliferative
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C144H257N51O31
Standard
Sequence
RGLRRLGRKIAHGVKKYGPTVLRIIRIA
Physicochemical Analysis
3198.90 Da
12.00
8.84
8.58
0.3158
-0.20
1.07
-0.20
27.00
125.36
0.0357
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1358.83
-10.54
52.0
41.0
111.0
226.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0174337 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 1056
4.6 μg/mL
MIC
PMID11600395;16997510;14742236;10601638;24221355;19396584 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
RECORD: Rec_0175702 VERIFIED: NO
Provenance & Taxonomy
Ovis sp. [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 8202835 B2 Evidence URLhttps://patents.google.com/patent/US8202835B2/en PatentUS 8202835 B2
RECORD: Rec_0186053 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella enterica serovar Typhimurium MS4252S
0.125 μg/mL
MIC
PMID11600395;16997510;14742236;10601638;24221355;19396584 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
RECORD: Rec_0189904 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus KCTC 1621
4 μM
MIC
PMID11600395;16997510;14742236;10601638;24221355;19396584 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11600395/
RECORD: Rec_0190054 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Pseudomonas aeruginosa
1.251, 0.626 μM
Crystal violet assay
PaperAntibacterial and anti-biofilm effects of cathelicidin peptides against pathogens isolated from cystic fibrosis patients PMID21849157 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21849157/
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