Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC539H873N147O165S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLGIGNASLTIDMNWNIRTWMFKDSGRGTVQISKVFVTAIFSTPLDNTGPMSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12180.84 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.13

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.01

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index17.92

Aliphatic Index 94.04

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4990.25

LogP -57.27

H-bond Donors 177.0

H-bond Acceptors 174.0

Rotatable Bonds 405.0

Heavy Atoms 855.0

Ring Count 16.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093081 VERIFIED: NO

Provenance & Taxonomy

OrganismAleadryas rufinucha [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria